It turns out the skin is an important battleground between dengue viruses and the immune system, according to research conducted at Duke-NUS Graduate Medical School and published in Science.
Currently, there’s no effective therapy for dengue, the most prevalent mosquito-borne viral disease afflicting human populations. That’s partly because the immune response following dengue virus infection is poorly understood.
This study found that T cells that are specifically located to the skin play an important role in the body's natural response to the virus. The finding suggests that triggering skin-homing properties could be important for developing a durable vaccine against dengue fever and related diseases.
Asian Scientist Magazine