Time for a New Pertussis Vaccine?

30 years after the introduction of the whole cell pertussis vaccine in the 1940s, few cases remained in the developed world—but now it is “probably the only vaccine-preventable disease that is currently on the rise,” writes Nicholas Carbonetti, associate professor of Microbiology & Immunology at the University of Maryland School of Medicine.

Bad publicity over side effects tied to the original vaccine led to a less reactogenic acellular vaccine, which induces an inferior type of immune response that has likely fueled the re-emergence, he explains. And, there’s a near-complete lack of effective treatments.

Carbonetti and others see a need to develop a new vaccine, and believe pertussis deserves far more research attention.
Oxford University Press Blog

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