New research finds that the HIV virus can survive and infect new target cells even after disappearing from the blood after ARV treatment. The study, which appears in Nature, has potential implications for delivering HIV drugs at effective concentrations.
Scientists from Northwestern University discovered a “sanctuary” harboring cells with low levels of HIV replication in cell samples from the lymph nodes of 3 patients who appeared to have cleared the virus.
"These findings are important as it is critical for the field of HIV cure research to know whether new infectious cycles are indeed continuing in patients on seemingly effective treatment," says Deborah Persaud, a professor of infectious diseases at Johns Hopkins University School of Medicine.
The Washington Post