Gravely ill and determined to release the herpes vaccine he developed, microbiologist Bill Halford didn’t want to wait around for grants and regulations. So he went rogue, shirking FDA regulations and gathering subjects at a hotel, and in Saint Kitts, to try his method. Halford’s promising research had inoculated mice using a weakened form of the virus. Some herpes patients, desperate for solutions, saw their symptoms abate—but for others, they worsened, writes Amanda Schaffer.
A troubled overseas clinical trial, conducted without FDA guidance, was panned by a medical journal. It also spurred millions in private investment, and lawsuits filed by trial participants.