Malaria Vaccine Passes the Test in Humans

A vaccine against fatal pregnancy malaria passed a phase 1 human-testing trial, according to promising results from Danish researchers.
 
Building on years of research, the team showed that the vaccine was safe and induced the right antibody response in a randomized, double-blind clinical trial published in Clinical Infectious Diseases. The discovery of a protein hook in the placenta of pregnant women that malaria parasites may attach to sparked their work.
 
Next, the researchers will work to document that it prevents pregnancy malaria in African women who would otherwise have contracted the disease, said the study’s lead author Morten Agertoug Nielsen.
 
University of Copenhagen

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