Dengvaxia: The Devil Was in the Delivery

Before the US FDA greenlit the world’s first dengue vaccine last week, Dengvaxia made headlines for a deployment in the Philippines that led to criminal charges.

After its 2016 rollout, concerns emerged that the embattled vaccine given to 100,000 Philippine children could potentially increase the risk of complications in children not previously infected with dengue.

While some 600 deaths remain under investigation, the WHO now says the vaccine is safe only for children previously infected with dengue.

The fracas has eroded vaccine confidence in the Philippines. From 2015-2018, parents’ belief in the importance of vaccines plummeted from 93% to 32%—while a major measles outbreak is underway.

NPR Goats and Soda

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