Drug-Resistant HIV on the Rise

A dozen countries across Africa and the Americas are experiencing an alarming uptick in resistance to 2 crucial HIV drugs: efavirenz and nevirapine, according to a WHO report that suggests countries switch to the drug dolutegravir, which is less prone to resistance.

The resistance is hitting infants particularly hard: From 2012-2018 in 9 countries, about half of newly diagnosed infants had a form of HIV resistant to one or both of the drugs.

The problem is also more acute among people who paused treatment for any number of reasons—from stigma to drug shortages—compared to first-time users.

Nature

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