Epilepsy Researchers Up Their Game

Lots of drugs are used for epilepsy, which afflicts 1 in 26 people in their lifetime and causes crippling seizures. But very often they don’t work.

One researcher described the treatment status quo as a game of whack-a-mole, using the same ineffective drugs to treat myriad forms of the disease.
So researchers are changing tack, searching for root causes and embracing advances in gene sequencing and animal modeling.
In San Francisco, researchers using genetically engineered zebrafish larvae to test treatments for various forms of epilepsy that affect young children. Others are delving into the role of inflammation in treatment-resistant cases.

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