Game-Changing “Megaphages”

“Megaphages” discovered by accident in Bangladesh have now been found all over, from pigs in Denmark to spit samples in California.
These enormous viruses carry as many as 735,000 DNA letters compared to a normal phage’s average 52,000—prompting researchers to rethink phages, which don’t cause disease in humans but rather infect and kill bacteria.
Regular-sized phages have already proven medically useful—these giant versions could be “a treasure trove of new biological functions, which can be tinkered with to make applications that are useful for medicine, industry, or the environment,” says Bonnie Bassler of Princeton University.
The Atlantic

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