Should Researchers Stop Attacking Amyloid?

They hoped that the drug would stop Alzheimer’s before it started—but “crushing” results have shown that 2 experimental drugs failed to slow cognitive decline.
The study, led by researchers at Washington University in St. Louis, involved healthy subjects with a rare genetic mutation that causes amyloid overproduction—guaranteeing dementia in their future.
The findings beg the question: Should researchers give up on amyloid-attacking drugs? After billions of dollars spent, many have failed.
But amyloid buildup is an undeniable step in Alzheimer’s progression, and researchers aren’t giving up yet. A fresh round of grants will support anti-amyloid treatments that start even earlier.
The New York Times

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