New Rumblings About Cytokine Storms

Early in the pandemic, many researchers pointed to immune system overreactions—“cytokine storms”—as a driver of COVID-19 deaths, neatly helping explain why some managed to clear the virus from their system, but still died.  
 
Drugs designed to block one particular cytokine known as “il-6” quickly became the standard of care. But the first rigorous studies suggest that if il-6 plays a role, it may be just one of many damaging responses, such as other inflammatory chemicals, blood clots, or possibly, according to one study, an attack on areas of the lymph nodes that produce antibodies.
 
Another Issue: There is no hard-and-fast definition or diagnostic criteria for “cytokine storms.”
 
The New York Times

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