In the US, reports of a rare blood clotting disorder in female recipients of the Johnson & Johnson COVID-19 vaccine have raised the possibility that the jab could be recommended just for men, The Atlantic reports.
All 6 cases were women under 50, making the possible role of estrogen in these clotting events is a hot topic.
Why? “The disorder”—cerebral venous sinus thrombosis—“is a collision between a powerful immune response and a naturally clot-prone environment; … the hormone estrogen can amp up both of these factors,” explains Katherine J. Wu.
But: The J&J shot hasn’t officially been identified as the cause.
And: A preoccupation with the sex of those suffering sideffects can obscure other potentially important factors like race, ethnicity, medical history, and social norms.
Take Note: Similar clotting cases involving the AstraZeneca vaccine in Europe involved some men and a range of ages, Anthony Fauci told CNN’s Dana Bash.
Fauci expects J&J to make a comeback—with restrictions or warnings—by Friday, when CDC advisers are set to discuss the matter.