Covid-19 Treatments: Coming Soon?

A "do not resuscitate" order is written on the window of a patient's room in the COVID-19 ICU in Grants Pass, Oregon. September 9, 2021.  Image: Nathan Howard/Getty
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A "do not resuscitate" order is written on the window of a patient's room in the COVID-19 ICU in Grants Pass, Oregon. September 9, 2021. Image: Nathan Howard/Getty

Vaccines, vaccines, vaccines… What about COVID-19 treatments?
 
More are in the works:
 
Pfizer announced yesterday it has launched a Phase 2/3 trial of an oral antiviral treatment (PF-07321332) with 2,600 healthy adults who share a household with someone who has a confirmed COVID-19 infection, Reuters reports.
 
The drug seeks to “block a key enzyme needed for the virus to multiply.” A low dose of an older medication used in HIV treatments (ritonavir) will be given with the new drug.
 
The Quote: “If successful, we believe this therapy could help stop the virus early — before it has had a chance to replicate extensively,” said Mikael Dolsten, Pfizer president.
 
Another treatment: Merck and Ridgeback Biotherapeutics have a late-stage trial ongoing of the experimental drug molnupiravir that seeks to prevent infection.
 
The Moonshot: A nonprofit, open-science consortium committed to affordable antivirals against COVID-19 has received £8 million ($10.8 million) in funding from Wellcome, DNDi said yesterday. The COVID Moonshot includes 150 scientists who are crowdsourcing ideas for molecular compounds with plans to evaluate them in-vitro against SARS-CoV-2. Clinical trials are expected to begin next year.
 
So far: The US has approved only 1 antiviral for COVID-19: Remdesivir, per Axios.
 

Related: A daily pill to treat COVID could be just months away, scientists say – PBS NewsHour

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