New Clues from Old Stool Samples

new study relying on a “treasure trove” of cryogenically preserved stool samples from the early 1980s is providing new insights into the gut microbiome’s relationship with HIV/AIDS susceptibility.

The study “could have implications for disease cure or even prevention," said co-senior author Charles Rinaldo, a University of Pittsburgh professor of infectious diseases.

In the study, scientists were able to use samples provided 30+ years ago by men whose friends were dying of AIDS — when scientists were struggling to understand HIV.

  • The new research found that some of those men who ended up contracting HIV had harbored a greater relative abundance of pro-inflammatory vs. anti-inflammatory gut microbes, compared to those who remained HIV-negative.

Science Daily

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