When researchers discovered a weed toxic to sheep showed promise against a rare genetic condition, Gorlin syndrome, a pharmaceutical company jumped to test it. 

The discovery of mental illness clusters within families has sparked genetic research—but the data has a diversity problem.   78% of current DNA data comes from people of European ancestries, who thus stand to benefit most from related treatment advances, write Anne…

Africa is home to the most genetically diverse population in the world. Yet just 2% of genetic materials used in pharmaceutical research comes from the continent; 90% comes from Caucasians.   Abasi Ene-Obong is looking to change that with 54gene, the first biobank of…

Tiny genetic variations have major effects on how drugs work in different people, but bias built into genomic research means prescribing algorithms are best-tailored to European genes—with consequences for everyone.

HOUSTON – Eric Boerwinkle isn’t your typical public health school dean. He manages six campuses as dean and M. David Low Chair in Public Health at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health. The main campus in Houston is a…

Women across the globe weighing a host of options for birth control never get a straight answer to a basic question: How will it affect me, specifically? You don’t know until you try, women are told.   For the 900 million women who use contraceptives worldwide, “…

Genetics influence a person’s susceptibility to substance abuse disorder but understanding epigenetic factors may be key in fighting opioid dependence.

A 7 year-old boy who lost 60% of his skin to a painful genetic disorder saw almost all of it restored with experimental genetic engineering of skin cells.   The remarkable achievement, published in Nature, could revolutionize treatment of burn victims and people with skin…

Eating disorders affect 30 million Americans—and are the most deadly of psychiatric illnesses—but they’re often stigmatized as “mind over matter.”

67% of US pregnancies flagged with a chromosomal abnormality are terminated. In Iceland, that number is almost 100%. With the rise of screening for genetic disorders, the island nation has nearly eradicated Down syndrome births. 80-85% of pregnant women identified as “high…