How did Purdue Pharma sidestep widespread criticism for so long? As suspicions—and lawsuits—mounted around its blockbuster painkiller, OxyContin, the company deployed a massive PR machine to second-guess bad press about opioids. Purdue funded studies, think tanks, and…

Before she died, Joshua Hunt’s grandmother’s painkillers began disappearing ever-more-quickly before his eyes, he writes.   The opioids were prescribed by the Southeast Alaska Regional Health Consortium—a lifeline for many Native Alaskans, and a source of opioids that a…

There’s a problem with US President Trump’s new plan giving states, wholesalers, and pharmacies a green light to import cheaper drugs from Canada: Canadians are not on board.   They say it will exacerbate their own drug shortage. Health officials and industry reps will meet…

When it comes to drugs, all pricing is not created equal. Far from it. In Greece, the pneumonia vaccine ranges from $9 per immunization to $168; France pays $189; Lebanon $243; India $60. These swings and roundabouts sum up a “broken” drug pricing system worldwide, says…

For expensive medications, pharmacy benefit managers like Express Scripts are a “middleman” intended to ensure that patients will benefit from prescribed meds. PBMs work supposedly to negotiate drug prices on behalf of insurance plans. But, according to many, PBMs are…

Tiny genetic variations have major effects on how drugs work in different people, but bias built into genomic research means prescribing algorithms are best-tailored to European genes—with consequences for everyone.

Opioid prescribing guidelines are harming patients with severe chronic pain, according to a letter by 300 medical professionals from across the spectrum of the opioid debate. The authors' “uneasy alliance” includes 3 former White House drug czars, pain and addiction…

Long suicidal, Joe Wright “almost immediately started feeling more hopeful about life” after taking Ketamine as part of a small Columbia University study.

By 2006, the average per person morphine consumption in Western Europe was 12X that of Eastern Europe—and the divide remains stark. Before the palliative care movement took off in the 1960s, Europe’s morphine consumption was more even.   A Soviet legacy and “tough it out”…

Puerto Rico’s opioid problem doesn’t compare to that on the US mainland—yet. In the wake of Hurricane Maria, the US territory could quickly catch up.