Tiny genetic variations have major effects on how drugs work in different people, but bias built into genomic research means prescribing algorithms are best-tailored to European genes—with consequences for everyone.

Opioid prescribing guidelines are harming patients with severe chronic pain, according to a letter by 300 medical professionals from across the spectrum of the opioid debate. The authors' “uneasy alliance” includes 3 former White House drug czars, pain and addiction…

Long suicidal, Joe Wright “almost immediately started feeling more hopeful about life” after taking Ketamine as part of a small Columbia University study.

By 2006, the average per person morphine consumption in Western Europe was 12X that of Eastern Europe—and the divide remains stark. Before the palliative care movement took off in the 1960s, Europe’s morphine consumption was more even.   A Soviet legacy and “tough it out”…

Puerto Rico’s opioid problem doesn’t compare to that on the US mainland—yet. In the wake of Hurricane Maria, the US territory could quickly catch up.  

Prescription heroin has shown promising results treating addiction in other countries—could it help quell America’s raging opioid crisis? The approach would be controversial in the US, but it’s worth a shot, found a new Rand Corporation analysis.

The skyrocketing price of life-saving prescription drugs mean scores of Americans must fork out thousands of dollars a month just to survive, or choose between crucial medications.Among them is 57-year-old Saundra Johnson, whose income is too high to qualify for extra…