Philippines villagers have deployed toads and mosquitofish to root out the larvae of Aedes mosquitoes behind the country’s deadly dengue epidemic that's caused 900 deaths and 209,000 cases this year.   The toads and fish face a formidable foe. “These mosquitoes are…

In Africa and Asia, 2 million women and girls live with obstetric fistula that leaves them incontinent.   The condition is “effectively a hole in the birth canal” resulting from lengthy, obstructed labor without key emergency care, Sarah Newey reports. In developed nations…

It sounds like promising news: The US and the Taliban are in talks to halt almost 2 decades of fighting in Afghanistan.   But when troops withdraw, what will happen to the aid that one of the world’s poorest countries relies on?  

From 2008-2018, a third of clinical trials that produced new cancer drugs failed to report the race of participants.A new study also found that even among trials that did, participation numbers were not representative of the general cancer patient population: just 6%…

The path from an ER visit or hospital stay to a courtroom lawsuit has become so familiar to the people of rural Missouri that they call it the “follow-up appointment.” Poplar Bluff Regional Medical Center is like many financially troubled rural hospitals. Facing $84 million…

Yesterday the FDA greenlit a hugely promising drug for a form of TB that has long been a death sentence, The New York Times reports.   Pretomanid is part of a 3-drug regimen that proved 90% effective against extensively drug-resistant TB, according to preliminary trial…

2 new Ebola drugs boast a 90% survival rate when administered shortly after infection, according to an unprecedented clinical trial in the DRC, reports Amy Maxmen in Nature.   Tested in Ebola hotspots, the drugs REGN-EB3 and mAB114 outperformed ZMapp—which had shown promise…

In the long battle against HIV, elite controllers have been held in awe.  They’re people who are HIV positive but maintain undetectable viral loads—they keep HIV in check without meds.  Researchers have tried and failed to engineer immune cells that would recognize and…

Ebola researchers in the Democratic Republic of the Congo have adapted to working in a war zone, Amy Maxmen reports in Nature. A massive vaccination campaign pivoted to deter attacks, researchers are rushing to complete genomic sequencing of virus samples, and an…

Living with a chronic inflammation disorder like arthritis is enough to make anyone depressed.   But mental health issues and chronic inflammation—which are rising in tandem—may be more closely related than once thought, emerging research shows. They appear to play off of…