25 years ago, Bill and Melinda Gates’s route to philanthropy was carved out by learning about scores of child deaths from diarrhea: “We were surprised, then we were outraged, then we were activated.” In their annual letter, the pair lay out some surprises of 2018:

WASHINGTON, DC—The day that Christy Turlington Burns became a mother is the day she became a maternal health advocate, she shared at a recent gathering of public health advocates.

Following yesterday’s dismal news of a yet another decline in US life expectancy, Michael R. Bloomberg announced today that he will put $50 million into helping up to 10 states fight the opioid epidemic over the next 3 years. The funds will support a unique collaboration…

The HIV/AIDS epidemic risks spinning out of control if current funding trends continue, according to Mark Dybul, a founding architect of PEPFAR.

Global progress against malaria disguises a stark rise in infections and deaths in African countries upended by conflict—but new strategies show promise in the fight, researchers said at a malaria conference in Dakar yesterday.

Making the case for going big, James Nardella, who serves as a principal at the Skoll Foundation, brought together panelists at the Global Health & Innovation conference to talk about one of the Audacious Project’s big ideas.

The smiling people on the project websites never tell the whole story—global health and development takes hard work, realistic goals, admitting to failure, and sticking around long enough to fix the problems, Jordan Levy told Unite for Sight attendees Saturday.

Allen County, Kansas, may be small—just 13,000 people—but the community’s big thinking on health and economic development attracted the attention of the Robert Wood Johnson Foundation. The county’s initiatives to bring new businesses to the area doubled as health…

Bloomberg Philanthropies has thrown $20 million behind a tobacco industry watchdog to monitor “dirty tactics” as it homes in on low- and middle-income countries and the e-cigarette business, writes Sarah Boseley. Stop (Stopping Tobacco Organisations and Products) comes amid…

Amid all the woes in the world, Bill and Melinda Gates hang on to hope. For their annual letter, they explain why—and tackle the 10 hardest questions they get.Highlights:#1: Why don’t you give more in the US? Melinda: “We don’t compare different people’s…