Modern medicine is facing the convergence of 2 major problems: the rise of antibiotic resistance and the fall of efforts to find badly needed replacements, write Allan Coukell and Helen W. Boucher. In 2018 alone, 3 Big Pharma firms halted antibiotics R&D; others have…

Drug-resistant bacteria are all over the news, but fungi are quickly—and quietly—threatening global health. Take Candida auris. More than 90% of C. auris infections have resistance to at least 1 drug, according to the CDC. From a Venezuelan neonatal unit to an…

For clues to map antibiotic resistance, sewers snagged the spotlight, a new study in ScienceAdvances demonstrates.  

Not much is known about efforts to address antimicrobial resistance—an issue that a new Global Research and Development Hub will tackle.   First conceptualized in 2017, the hub—based in and funded by Germany—consists of a 5-person team initially focused on creating a…

“Antimicrobial resistance is a more immediate threat to human health than climate change,” writes epidemiologist Steffanie Strathdee, and it’s worsening with overuse of antibiotics and a lack of alternatives.   Phage therapy—using bacteriophages, or viruses that only attack…

A new report details a waterborne multidrug-resistant bacterium, Sphingomonas koreensis, that can creep through plumbing via slime or cling to life in sink parts. Moreover, the organism that caused pneumonia and blood, skin and urinary tract infections in 12…

Gaza has become a central breeding ground for superbugs that are sweeping modern conflict zones, threatening health security worldwide with infections that know no border. The scourge is beginning to resemble the days before penicillin saved millions from death and…

Global antibiotic use among children varies widely among countries, but with no clear divide between high- and low-income nations.   Yesterday, The Lancet Infectious Diseases published the first attempt to estimate antibiotic use by under-5s at the country level. Beyond…

Manufacturing antibiotics is tricky: They’re as pricey to make as any other drug but, unlike meds for cancer or chronic illnesses, they’re curative. That means limited doses are required for success. Their profitability is also curbed by antibiotic resistance that forces…

Mycobacterium tuberculosis’s ability to develop resistance to antibiotics has long been a threat to global health. Matthew Wipperman, PhD, MSc, a research scientist in the Immunology Program at Memorial Sloan Kettering Cancer Center, and colleagues recently published a…