Last night Purdue Pharma filed for Chapter 11 bankruptcy to move forward a settlement that would shield the Sacklers and the family firm from over 2,600 opioid lawsuits, The New York Times reports.

One of the most painful marks of the US opioid crisis is the lack of safe, evidence-based treatment options for the people trying to escape addiction’s stubborn grip. The first article in a must-read Vox series on addiction treatment includes the story of a South Burlington…

As many as 250,000 newborns exposed to opioids in utero are caught in a legal tussle between lawyers seeking a separate trial for them and a judge who has rebuffed their requests. As a nationwide prescription opioid lawsuit heads to trial in a couple months in Ohio, lawyers…

76 billion.   The number is far beyond human imagination—but not for America’s drug companies, which sold 76 billion oxycodone and hydrocodone pain pills from 2006-2012.   A US district judge in Cleveland on Monday ordered a portion of a massive government database opened…

A swell in opioid-related bacterial and viral infections is further compounding the crisis.  Upticks in HIV, hepatitis and bacterial infections—including antibiotic-resistant Staphylococcus aureus—are alarming public health officials. Most result from unsanitary injections…

Drugmakers, doctors and regulators have been blamed by many for America’s opioid crisis. But judges are also culpable, a Reuters investigation found.      Numerous judges who have—and are—adjudicating cases against Purdue Pharma have allowed damning evidence against the…

David Sackler says his family isn’t to blame for the opioid crisis. In an exclusive interview with Vanity Fair, Sackler hit back against widespread accusations that the family firm, Purdue Pharma, spurred the crisis with aggressive and misleading marketing of OxyContin.

Buprenorphine can be lifesaving for people with substance use issues—but only if they can get it.In a new Annals of Internal Medicine study, researchers posing as heroin users called 546 prescribers in states with the highest overdose death rates.

Across the US, the number of babies born in drug withdrawal has spiraled. As they become school age, teachers are facing challenges for which there is no steadfast protocol. “They’re just these damaged little brains that are not psychologically ready to learn,” says…

A landmark trial beginning today in Oklahoma will delve into the origins of the opioid crisis that’s killing 130 people a day, Politico reports.