76 billion.   The number is far beyond human imagination—but not for America’s drug companies, which sold 76 billion oxycodone and hydrocodone pain pills from 2006-2012.   A US district judge in Cleveland on Monday ordered a portion of a massive government database opened…

A swell in opioid-related bacterial and viral infections is further compounding the crisis.  Upticks in HIV, hepatitis and bacterial infections—including antibiotic-resistant Staphylococcus aureus—are alarming public health officials. Most result from unsanitary injections…

Drugmakers, doctors and regulators have been blamed by many for America’s opioid crisis. But judges are also culpable, a Reuters investigation found.      Numerous judges who have—and are—adjudicating cases against Purdue Pharma have allowed damning evidence against the…

David Sackler says his family isn’t to blame for the opioid crisis. In an exclusive interview with Vanity Fair, Sackler hit back against widespread accusations that the family firm, Purdue Pharma, spurred the crisis with aggressive and misleading marketing of OxyContin.

Buprenorphine can be lifesaving for people with substance use issues—but only if they can get it.In a new Annals of Internal Medicine study, researchers posing as heroin users called 546 prescribers in states with the highest overdose death rates.

Across the US, the number of babies born in drug withdrawal has spiraled. As they become school age, teachers are facing challenges for which there is no steadfast protocol. “They’re just these damaged little brains that are not psychologically ready to learn,” says…

A landmark trial beginning today in Oklahoma will delve into the origins of the opioid crisis that’s killing 130 people a day, Politico reports.

Buprenorphine—“bupe”—is one of few proven opioid addiction treatments. The daily pill can be taken for months or years at a time and is coupled with counseling and regular health care provider visits. But a recent study found that 35X more white patients than patients of…

The first clinical trial of deep brain stimulation for drug addiction launched in Shanghai and may be heading to the US. In the past, DBS—surgical implantation of a device in the brain that can electronically stimulate specific areas—has yielded mixed results. A recent…

Yesterday, US health officials pledged $350 million to study local solutions to the opioid crisis. The 4-state effort will home in on selected communities, aiming to reduce their opioid-related overdose deaths by 40% over 3 years, Reuters reports.